Seminal fluid improves fertility women and improves IVF pregnancy rates

o-SPERM-FERTILITY-facebookSeminal fluid is often viewed as simply a vehicle to carry sperm to fertilize the female egg, but a more complex function in influencing female reproductive physiology is now evident
Remarkably, seminal fluid contains special signaling agents that interact with the female reproductive tract to prime the immune response, with consequences for fertility and pregnancy outcome. This research isn’t new and we have spoken about this in previous posts. But we now know a bit more about how sperm may assist in implantation for, especially for IVF.

See our other post http://shentherapies.com.au/sex-around-the-time-of-embryo-transfer-increases-the-likelihood-of-successful-early-embryo-implantation-and-development/

Recent studies demonstrate a key role for seminal fluid in enabling  embryo implantation and optimal placental development. In particular, seminal fluid promotes health immune responses which facilitate embryo implantation by suppressing inflammation, assisting uterine circulation and blood supply and also protecting the embryo.

There is emerging evidence  where seminal fluid provokes an adaptive immune response in the cervical tissues after contact at intercourse, and spermatozoa accessing the higher tract potentially affect the endometrium directly. Research has now shown that sperm and seminal fluid actually help with endometrial receptivity, which is needed to create the right environment for a healthy embryo to implant.

These biological responses may have clinical significance, explaining why

[1] intercourse in IVF ET cycles improves the likelihood of pregnancy

[2] inflammatory disorders of gestation are more common in women who conceive after limited exposure to seminal fluid of the prospective father

[3] preeclampsia incidence is elevated after use of donor oocytes or donor sperm where prior contact with conceptusalloantigens has not occurred.

Research like this is important to define the mechanisms through which seminal fluid interacts with female reproductive tissues, to provide knowledge that may assist in preconception planning and infertility treatment. It also bring attention to the fact that couples still need to be engaging in regular intercourse during IVF cycles to help not only with implantation, but to increase pregnancy rates through optimization on the endometrial lining through contact with seminal fluid. Regular intercourse also promotes connection and bonding for the couple as well and this is something that is very much overlooked.

Shen Therapies offer a Fertility Program where couples are educated on important factors such as this… and more

If you would like to find out how you could improve your chances of having a baby, please give Shen Therapies a call and ask about our highly successful fertility program that has helped over 12,000 babies (and counting) into the world and can increase a couples chances of conception by 96.1% *

For more information on our highly success fertility program, see also http://shentherapies.com.au/shen-therapies-highly-successful-fertility-program/

Alcohol & Binge Drinking May Cause Breathing Problems & Problems with Your Lungs.

alcohol affecting your health

 

 

 

 

 

 

Alcohol affects nearly every major organ in the human body, including the heart, the brain, the liver, pancreas, and kidneys. A team of researchers from Loyola University has found that binge drinking may be the reason it’s hard to catch your breath and can also make it harder for the lungs to breathe.

A recent new study has revealed that excessive alcohol consumption  affects the balance of nitric oxide levels in the lungs. Nitric oxide is a naturally produced gas that helps fight bacterial infections in the lungs. The Study revealed that the more a participant reported drinking, the lower their levels, which then showed that their bodies were less equipped to kill bacteria and fight off lung infections. Excessive alcohol drinkers were considered women who consumed more than one drink a day on average and men who had more than two drinks a day. This criteria alone, of what excessive drinking is, is going to shock people as many Australians and Americans drink way more that this daily.

The study’s lead author Dr. Majid Afshar, a pulmonologist at Loyola University’s School of Medicine commented that “Alcohol appears to disrupt the healthy balance in the Lung and Lung doctors may need to take this into consideration.”

One out of every four Australian and Americans drinks to excess and this leads to a frightening statistic of six alcohol poisoning deaths every day. Researchers will continue working to unravel the complex relationship between alcohol consumption and the human body.

The safe alcohol limits are defined as 4 standard drinks per week for a female and for men it is 2 standard drinks in one sitting, with at least 2 alcohol free days per week.

Next time you are struggling for breath, just remember it might be the amount of alcohol you are drinking. It may also mean you need to drop the drink and get fit and healthy too. Let’s not forget that many alcohols contain preservatives and sulphytes that may also cause breath problems too. Like I always say, a little bit of alcohol (mainly red wine) is good for the body, but a lot of it is going to cause problems with your health.

A Special Kind of Pill for Better Health and Increased Fertility

Chill PillSeveral weeks ago I mentioned that I was going to talk to you all about a special medicine and a special kind of pill, that can not only help you with gynaecological and other healthy issues, but it can also help with fertility and being able to fall pregnant. I was going to post this up straight away, but then I had to think more about it, because I know when you mention this subject, people can take a message with the intention of helping the wrong way.

So what is this special pill that I am talking about and not yet available on the market?

Well, it’s called a “Chill Pill” and many of us need to be taking it often, or learning to administer it often.

Now, before anyone gets all up in arms about this and what I am about to say, I need you to listen and take the personal out of this and just hear the reasons why. I have been on the other end of stress, where it almost killed me, literally and I know how it then affected my health and then exacerbated pre-existing health complaints I had. So I am coming from a place of understanding, but also a place of wanting to help people through my own experienced personally, but also what I see in clinical practice daily. I was one of those people who kept saying that weren’t stressed, or that I don’t feel stressed, yet all the while my body signs were saying something different. Like any change we need to make, the first part is admitting there may be something wrong in order to enact that change.

The sad fact is that 9 out of 10 people report being stressed and 41% of people feel they experience unhealthy levels of stress. Stress and the body’s response to it, can affect people in different ways. Small amounts of stress that are easily resolved can help to keep us motivated and achieve our goals. The difference with long term or chronic stress is that it can affect the whole body in a negative way. It is the long grade, low grade stress (or busyness) that often creeps up on us and causes issues. Many people do not even know they are stressed, or that stress is a big factor in their current health issues, because they are either so used to it, or their health issues takes over and they cannot even begin to see the correlation.

The harsh reality of many problems in life is that we are ultimately responsible for our own well-being. Not all people will want to accept this, as it is so much easier to blame someone or something else for our dilemmas.

Nearly every problem we experience in life may have an element of stress to it bought on by ourselves and our busy lives, with many of us not consciously knowing it is at play. That means everything from a common cold to a long-standing illness. Everyone reading this will be by now squirming in his or her seats as the harsh reality of such a statement hits home. But the real problem with this is that it is true. I know I had to face this reality with my own health issues. We do cause many of our own health problems, or exacerbate them, either consciously, or subconsciously.

The problem with any health matter is getting people to become responsible for their own self. So much illness is completely preventable if we would just take responsibility for our own actions. It is so much easier to blame someone, or something else with comments such as “ I have tried everything”, “That didn’t work for me”, or “I’ve been everywhere and nothing can help me”. The problem with many of these statements is that they are all just excuses not to take responsibility for our actions. Maybe it isn’t that the methods you are trying aren’t working. Maybe it is simply a matter of nothing will ever work unless we make that all important change for ourselves first. Sure, some disease states are hereditary, or someone have a predisposition for them, but even so, once the illness, or disease is expressed in the body, it is our responsibility to do what we can to control it. Yes, sometimes it doesn’t seem fair, I get that, but sometimes you just have to admit there is an issue that isn’t going away in a hurry, or keeps being flared up, because you need to make some changes in your life to better manage this issue. I know this is something I had to learn myself. Boy did I fight the reality of this in the beginning too.

Stress is also a major factor in many couples not being able to conceive. Stress affects cortisol levels and the adrenals and this then has an effect on testicular and ovarian function. Stress can affect both sperm and egg quality and high stress levels also affects our hormones and our immune system. Stress also has an effect on the uterine environment, which can affect implantation, affect circulation in the uterine lining, activate high number of natural killer cells and also increase the risk of miscarriage. High stress levels also exacerbate, or fuel many gynaecological and men’s reproductive health issues too.

Looking for the ‘Off ’ Butt on

Stress can affect each of us differently. Perhaps you are suffering from anxiety, feeling worried, depressed or irritable; even feeling exhausted and overwhelmed can indicate you are under stress. As well as affecting your ability to cope, stress may also be causing a disruption to your health. When under stress for a length of time, you may be more susceptible to tension headaches, high blood pressure, frequent colds and flus, digestive disorders or a worsening of an existing condition. So you can see, there are many reasons why it is so important to manage your stress now, take that “Chill Pill” before it starts impacting your health and wellbeing.

How Resilience Begins

Some people seem to deal with stress better than others. That doesn’t mean that the rest of us need to continue suffering. The ability to increase your resilience to stress is something that can be learned and helped with talking to a counsellor, or psychologist etc. There are supplements, nutrients, and vitamins to support your body’s individual stress response system too. Many people are lacking key nutrients because of our highly processed diets now and we also know that gut health, and a healthy microbiome is integral to psychological wellbeing and our moods. Taking a strain specific probiotic and a prebiotic daily can improve gut health and improve your immune system and psychological wellbeing. Omega 3 oils, multivitamins, melatonin, St John’s wort, passion flower, chamomile and many other herbs and nutrients can assist with coping with stress and its impact on the body. Don’t buy vitamins or supplements off the shelf at the chemist or supermarket as these are so inferior and contain lots of fillers and additives that aren’t good for you. Always see a qualified healthcare practitioner to get proper advice on what nutrients and supplements are needed for your health complaint. By the way, Dr Google is banned in my clinic. Dr Google is not a reliable way to find out about healthcare products and illnesses. Only a trained healthcare professional should be giving you that advice.

Some people may be in such a bad state that medication may be needed to get them over their first hurdles and develop some resilience and coping skills. This should always be done in conjunction with talk therapy as well. To be honest, most of us could do with talking to a good counsellor or psychologist to get some coping strategies to deal with work, business, health, or life better.

Lifestyle Tips to Help Manage Stress

Managing your stress is essential for long-term health and vitality. With proper support, a variety of stress relief techniques can be introduced, in conjunction with a

healthy eating plan to help you stress less. These may include:

  1. Exercise: Daily movement is essential for brain health. Aerobic exercise including running, swimming or walking is proven to decrease stress hormones. Resistance exercise is also great for stress relief, burning fats, increasing lean muscle and keeping you healthy.
  2. Enjoy the benefits of spending some time in the sun. Being in nature for 30 minutes per day can help reduce stress hormones and assist recovery after a stressful situation.
  3. Meditation and/or yoga can help to increase relaxation whilst benefiting not just the mind, but also the body. Learning to unwind is important for reducing stress.
  4. Favourite pastime: create time for YOU! Do something that you love, like listening to music, enjoying a candle lit bath, watching a movie, or starting a creative project – these fun activities can help you become more tolerant of everyday stress.
  5. Get creative and express yourself in as many different ways as feels good; singing, dancing, and art projects are but a few ways to do this.
  6. Eat seasonally, fresh and organic as much as possible. Include protein at every meal with a variety of fruit and vegetables.
  7. Include good fats such as omega 3s from fish, nuts and seeds, and olive oil to help with brain health and mood regulation.
  8. Drink plenty of water, a minimum of eight glasses per day and avoid excessive alcohol, caffeine, sugar and salt.
  9. See a counsellor, or psychologist to get some coping strategies in place.
  10. Acupuncture has been shown to be as effective as medications for stress and equal to the effects of talk therapy in several major studies.

Stress Less for Good Health

Our modern lifestyle is inescapable. The stress of it however, is manageable. This is why I mentioned the magic “Chill Pill”. All people have to do is take the advice and administer it often. You aren’t born stressed and being stress isn’t a part of you. It is a learnt behaviour that can be changed. You can become more resilient to the symptoms and long term effects of stress through the aid of individualised lifestyle and dietary changes, together with nutrients, supplement and in some cases medicines that your healthcare provider can help you with. Talk therapy such as counselling and psychology is an integral part of leaning to cope with stress and dealing with it better too. Supporting a healthy stress response will allow you to feel more energised, resilient and ready to tackle life, so you can maintain the state of health and wellness that you deserve. I hope that helps everyone and please remember to take off those superwoman/superman capes regularly, allow space to just breath and shut off the mind and just have some you time. It is OK to just sit there and not feel guilty about it. People need to learn to switch off the “busyness” and close down the 100 boxes they have open. It is Ok just to sit in peace and quietness and not feel guilty about it. Actually, your body needs to do this to maintain your inner health, but also your psychological health.

When was the last time you allowed yourself the space to just be, just take some quite time and let the world pass by for a little while without worrying about it?

Take care and relax and don’t work too hard. We work to live, not live to work.

Regards

Dr Andrew Orr

 

Are Gluten Free Products Healthier For Us?

Are Gluten Free Products Healthier For Us?

Each day we are seeing more and more gluten free products lining the supermarket shelves. Today you can get everything from gluten-free bread, chips, pizza bases, cookies, cakes and other gluten-free products. But are there benefits to cutting out gluten, which is found in most of our grains such and wheat, oats etc?

While many consume gluten in many of the foods and products they are consuming daily and don’t realise the the affects on their health and digestive system, for many it is also a molecule that can wreak some serious havoc when consumed by the wrong person. But while many people look at gluten free products as now being a health food, the fact is that many of the gluten free products people are consuming, have more additives, have less vitamins and minerals, and contain more sugars than the gluten containing products. Should we just be going grain free instead of trying to use gluten frre products? Are these gluten free products healthier for you?

With marketing focussing more and more on the sales of gluten free products and the high prices that are charged for these products, we really need to look at what are in these products and ask the question…… Are these products really healthier for us?

I would say no, but let me explain why.

What Are Grains and What Do They Do To Our Health?

The word “Grains” does cover many of the common foods we eat now. Grains include wheat, corn, rye, rice, barley, oats, amaranth, buckwheat, millet and sorghum – and many others. These grains are used in so many products these days and part of the reason we are having so many problems with health issues. Bread, pasta, breakfast cereals, cakes, biscuits, pastries, crackers and so many other refined products consumed by many of us are all made with these inflammatory grains.

Let’s not forget that we give grains to cattle and livestock to fatten them up, make them grow faster (due to the hormone response from insulin) and add more fats into the meat for extra flavour.

The grain is the reproductive part of plant; it therefore needs to protect itself to enable future generations. The big difference with fruit; which is designed to be eaten by humans, is that when digested seeds are consumed, they are then spread further to ensure future generations.

As part of this overall protective mechanism, grains contain anti-nutrients, such as phytates, lectins, and other incomplete proteins. This is our major problem with grains. Even when gluten is removed from food products, these other inflammatory agents remain and most people are complete unaware of this and how much they are causing problems with their health and disruption to their digestive systems.

Phytates bind to minerals, vitamins and enzymes preventing them from being absorbed in your body. The Lectins found in grains have a significant impact in the gut, resulting in inflammation and poor absorption of nutrients – as well as insulin & leptin resistance. The inflammation that these anti-nutrients cause, is now known to be the cause of many modern diseases. But lets not forget that many of our grains that we consume daily are also genetically modified and this in itself is causing major disruption to our health and bodily functions. This alone could be a major factor in the increase of many disease states we are now seeing.

Refined grains are converted to sugar very quickly, which requires insulin to bring down the blood sugar level in the blood. High insulin levels cause the body to store fats and then stop the burning of fats. The high insulin also causes inflammation and insulin resistance – which is the cause of many of our health conditions. It can be the cause of anything from PCOS, Endometriosis, Depression, Diabetes, Heart Disease and many other health issues in this modern day. Consuming such a high carbohydrate load with every meal results in unstable, fluctuating blood sugar levels and this then results in hunger that is satisfied by consuming another high carbohydrate meal.

There is also differences between what we term as “Carbs”. “Good carbs” are fresh fruits and vegetables and naturally growing foods in their normal form. “Bad Carbs” are basically anything that is refined – (Breads, cereals, flour products, sugar and most of our packet based foods)

So What is Gluten and why is it so bad for our health?

Gluten is another protein that causes a lot of problems and is found in wheat, barley, rye, spelt, kamut, and oats (other grains have similar, troublesome proteins). Gluten is the only protein in food that’s indigestible and those who suffer from celiac disease experience adverse side effects from consuming  and — in severe cases —  touching  gluten. Gluten can slip through the intestinal lining, causing chronic damage, inflammation, nausea, diarrhea, stomach pain, and vomiting in these sufferers. There’s also evidence suggesting that people without coeliac can have a sensitivity to gluten, which still causes complications and forces them to live on a strict gluten-free diet. Whilst a lot of people may test negative for the autoimmune disease Coeliac, there is evidence to suggest most people do not handle this incomplete protein well.

Gluten causes gut irritation and inflammation and many people will not even realise that their problems are caused by gluten. Gluten has been linked to many autoimmune and health conditions.

The problem with Gluten Free products is that they are still highly refined and they still cause inflammation, due to high insulin, even with the gluten removed. The inflammatory lectins and leptins are still there too. Many gluten free products are also full of additives, fillers, binding agents and lots of sugar. Currently, there are no medications, treatments, or cures to successfully treat any form of gluten intolerance. But so long as they don’t consume any foods containing gluten molecules, both coeliac disease and gluten sensitivity sufferers can live a relatively normal and otherwise healthy life.

But the bottom line is that Gluten-free diets don’t necessarily mean you’ve chosen a healthier route when you run the risk of losing out on essential nutrients.

This is why a grain free, not gluten free, is the best option. If you truly want to be gluten free, just don’t eat the wheat grain, or other gluten containing and inflammatory grains in the first place. The best thing any person could do for their body, as the first step towards better health, would be to cut wheat grain from their diet completely. You will be much healthier for it in the long run.

If you do want to know more about how to follow a wheat free/grain free diet, then give Shen Therapies a call and book in a health and wellness consultation today.

Are We Over-Feeding Our Children and Killing Them with Kindness?

obese child

 

 

 

 

 

 

 

Ever year of practice, I see children becoming more over weight, more sedentary and being sick more often. Even the children that are not overweight are suffering from more compromised immunity and being set up for an adulthood impaired by illness. Many children see even come into my clinic eating countless packets of tiny teddies, crisps, lollies and all sorts and mum and dad are trying to tell them that the children eat a balanced diet, or they cant understand while their child is sick all the time. Some children quite literally have not eaten vegetable, or fruits and only eat small selections of packet and highly processed foods.

We have gone from letting children climb trees, play in the streets with friends, climb on play ground equipment and hovering over their every move, for fear they may be in danger, or hurt themselves. Thus the term “Helicopter Parent” is born

While we have gone from over protect them in the playground, we have gone to under protecting them in the lunch box, breakfast bowl and dinner plate. While being over concerned about how they may, or may not die in the playground, we are actually starting to slowly lead them to an early grave through the kitchen and their bellies.

Before we go any further, I do know that there are parents with children that do have genuine special needs and how hard it can be for them to make changes. But, even so, I have seen many of these parents make small changes for the better of their children. So if they can, we all can. Plus, there are always circumstances that are contrary to what I am talking about, I get that, but this is more about other children and other parents, who actually do have a choice in what they are putting in a child’s mouth.

Children are now eating more refined foods, more inflammatory grains, more junk foods, more sugars, more sweet drinks, more processed foods that every before. What once was a treat a few times a year, is now a staple foods source for many children and adults. While children once rode bikes and played in the playgrounds and streets, they are now sedentary and the only exercise they get is with their fingers on the controller of the play station, or X-box. Because of this, children’s muscles aren’t being moved properly, they are developing properly, they are more immune compromised and many just are not getting the vitamins, amino acids, proteins, good carbohydrates etc, needed to maintain proper health. Many children are now eating over 100gms of sugars in their diet daily.

Parent’s seem to come up with all sorts of excuses as to why their child eats the way they do, yet never seem to be taking control and actually doing something about it. Denial, defeat, blame and just not wanting to deal with the cries and demands of a child that hates change is all too much and thus the cycle continues. We bury our heads in the sands, the wine glass, the TV, the social media scene and pretend that life is grand. Many parents will even try to convince you that their child will eventually shoot up, lose the puppy fat, grow out of their fussiness and be OK. But, all the while each year their child has grown more overweight, had more illness and cant even walk to the end of the street and back. We are quite literally failing our children, by giving into them and their every demand. Like I said before, if parents with special needs can make changes to a child’s diet and lifestyle and make the effort, often under difficult circumstances, then we can make those changes for other children. It is a choice. But this isn’t about judging parents either. This is a point of saying that they need help, they need to change and educating them on what they need to do to help their child’s future. Help is always here, if you want to receive the help that is being provided.

Childhood obesity is a growing epidemic that not only puts children at risk for a lifetime of type 2 diabetes, heart disease, cancer, infertility and many other health issues, but it also creates a huge financial strain on our health system as well. According to a new study published in the journal Obesity, one out of every four children in Australia is overweight, or obese by the time they start school, and it’s costing our health system millions of dollars each year.

In this study, researchers from the University of Sydney in Australia collected all of the medical tests, diagnostics, medicines, and hospital admission data from 350 children in Australia at ages 2, 3 and a half, and 5 years old. They found that the health care costs for obese and overweight preschoolers were 60 percent higher than costs for healthy kids. Obese and overweight children were also nearly three times more likely to be admitted to the hospital for respiratory disorders, ear conditions, nasal issues, colds, flu’s and other disease states, due to poorer immune systems.

The study’s lead researcher Alison Hayes, associate professor of health economics at the University, has stated, “Childhood obesity is a serious public health issue, and is becoming an increasing problem in children under five years old. In addition to the health impacts of childhood obesity, there are major economic impacts, which may occur earlier than previously thought.”

She also says, “We know that children who are obese, or overweight, in early childhood are more likely to be obese, or overweight in later in the their childhood, adolescence and adulthood, which can lead to serious chronic diseases that have a huge impact on our health care system. This can also have impacts on families and future generations too. Early prevention of obesity is important to improve children’s health, but we need to be having more prevention and education to ease the costs and burden on the healthcare system too. We really need to get serious about this crisis in our nations health and start to take our heads out of the sand about an increasing worrying epidemic.

The researchers also noted that throughout the world, 6.9 percent of children under the age of five are either overweight or obese; however, countries such as Australia, America, and the UK have rates as high as 23 percent. According to the Centers for Disease control and Prevention, over the last 30 years in America and countries like Australia, obesity has nearly tripled among children and quadrupled among adolescents.

Children are now being raised in a world that is very different to what it was in our parents generation, 40 to 50 years ago. Parents are now feeding children more refined foods, more junk foods, more sugars, more grains, more fast foods, more sweet drinks, more sugar drinks etc, than every before. What once was a treat to a child 40-50 years ago, is now an every day occurrence, with many children consuming processed foods, sugary foods, grains, and junk foods with every meal. It is really out of control. Some children are not getting fresh foods and sustainable foods in their diets at all. Some children do not even know what some of the basic fruits and vegetables are.

We have become all too lazy when it comes to feeding our children. Childhood obesity is a disease of the environment. It’s a natural consequence of normal kids with normal genes being raised in unhealthy, abnormal environments and this was one of the findings of this landmark study.

According to the Obesity Society, overweight and obese preschoolers are five times more likely to grow up to be overweight and obese as adults. The most recent estimated annual medical costs for obese adults were $1,429 higher than those of normal weight adults. In order to lower the rates of obesity in future generations, we really do need to be looking at preventive measures and better education for children and their parents. We do know that many obese, overweight and unhealthy children have parents that over also overweight, obese, or have unhealthy eating habits and sedentary lifestyles.

This ever-growing issue might seem complex, but we need to start really looking at ourselves as parents and we also need better education in schools and the educations systems. The solution to lowering obesity rates and soaring healthcare costs is teaching adults and healthcare professionals what a healthy diet. We need to be looking at preventative measures and being more proactive, rather than reactive.

We need to get parents of overweight or obese children to consult with a qualified nutritionist and show these parents on ways to improve their everyday diet, which includes cutting empty calories and foods high in bad fats and added sugars. We need to educate parents what an actual good diet looks like and start following more of a clean eating, grain free, lower GI, primal based diet. When parents often question the use of grains and refined foods, I often ask them “How do we fatten up cattle???? ….. We Feed them grains”

Besides teaching adults and children to be eating better, we also need to teach them to be healthier on the inside, as well as outside and also the importance of exercise and also accessing healthy vitamins, probiotics, prebiotics, omega oils, amino acids and drinking water. Good education about eating starts at home and we can’t keep blaming others for all of our problems. These days we have more access to online education about our health than we ever have. It is time we take our heads out of the sand and start admitting that we have a big problem that every parent needs to recognize along with all our healthcare providers as well. We also need some of the organisations promoting health care to get with the program and stop promoting out of date education that is actually increasing the health crisis, not helping it.

At Shen Therapies, we can help parents with diet and lifestyle choices and help keep their children healthy into adulthood too.

Source: Hayes A, Simpson J, Chevalier A, D’Souza M, Baur L, and Wen LM. Early childhood obesity: Association with Healthcare expenditure in Australia. Obesity. 2016.

Excess Body Fat Can Cause Gynaecological Conditions, Lead to Menstrual Irregularities and Also Lead to Infertility

Metabolic table

 

 

 

 

 

 

 

When women come to see me for help with gynaecological conditions, or couples come to see me for help with having a baby, one of the first things I ask all of them to address is excess body fats and look at diet and lifestyle modifications. Women, men, and couples who are underweight, need to look at this also, because being underweight can be just as bad as being overweight, but for the purposes of this post, we are going to look at how excess fats can not only interfere with fertility, but they can be a major driving factor in gynaecological and men’s health conditions that many face on a daily basis. Worse still, excess body fat can also lead to many cancers that both men and women get also.

One of my biggest challenges with men, women and couples is getting them to look at how excess body fat is playing a big part in their current health, the gynaecological condition they have, or how it is affecting their fertility. I always get all sorts of excuses from “My friend was overweight and he/she does not have my condition”, or “The next door neighbour is overweight and she has had 3 children” and all many of excuses that seem to be a big block in actually taking responsibility for one’s health. I get that it can be hard to get started and hard to make the steps for a better life, but at the end of the day, all these things I hear are just excuses really. Yes, the next door neighbour may not have your health issue, but they may also have some other health issue, or be at risk of another health issue. Yes, your friend might be overweight and has had a couple of children easily, but they may also be younger than you and many of the health issues they face because of their weight may not have caught up with them yet, but it will. I always have to get people to stop focusing on others and get back to looking at themselves, because other people are different. Other people are not you. We are all different individuals with different weaknesses in the body and what may affect one person, may not affect another, but this does not mean we can sit back and just do nothing about our health, or keep comparing our life to another.

Looking at a person’s overall weight is paramount for any health condition that the body faces and we need to look at the individual, not at the masses. Research shows us that excess body fat can lead to diabetes, heart disease, cardiovascular events, cancers, gynaecological issues, infertility, men’s health issues and many other complaints in the body. It can also lead to an early death too. This is a fact and no matter how many excuses people want to make, nothing is going to change the fact that excess body fat is not good for us and it causes problems with our health and now costing the health systems dearly too.

Excess body fat produces excess estrogens in the body and we are now calling these “Obestrogens”. These excess estrogens can not only have an effect on testicular and ovarian function, but they also interfere with other hormones, increase inflammation in the body and then add as drivers for other health issues in the body. These “Obestrogens’ can also interfere with your DNA and can also be passed on to your future offspring through the DNA of the sperm and eggs and also pass genetic conditions onto them as well.

Eating too many grains, sugars, alcohol and refined foods are a big cause of excess fats in the body. These foods lead to increased blood sugar levels, which in turn lead to excess insulin in the body. This then leads to the body storing fat and also stopping the burning of fat. This then leads to high levels of inflammation in the body and a big driver behind many of the major health complaints in the body and even our leading causes of death, in both men and women. When people ask me how refined foods and grains lead to excess fats I also ask them “How do we fatten up cattle and livestock?” The answer is we give them high amounts of grains which increase hormone levels, which then lead to excess growth and also lead to higher amounts of fats in their bodies.

Excess body fats are a big contributing factor in PCOS, Endometriosis, Fibroids, Cysts, Polyps, Sperm quality issues, Prostate issues, Diabetes, Infertility, Cardiovascular disease, Heart disease and Cancers in both men and women

For women excess body fat can lead to menstrual irregularities and heavy periods too, without necessarily having a known gynaecological condition. These excess fats produce estrogens, which is needed to thicken the uterine lining. But when there are too much circulating estrogens, the lining becomes too thick and unstable, eventually leading to bleeding. This can be unpredictable, and often very heavy, lasting a long period of time. These excess estrogens can then lead to gynaecological conditions such as PCOS, Endometriosis, Fibroids etc, but they can also be a big contributing driver of cancers in women.

These excess fats can also lead to men growing breasts, feminisation, having prostate cancers, prostate issues, sperm issues, diabetes, heart disease, infertility, erectile dysfunction, and many cancers that men face.

With many of the developed western countries have a population with over 70% of its people being overweight, or obese, now more than ever we need to look at ways of educating people about eating better, exercising more and looking after their health. While we need governments to intervene, we also need people to take personal responsibility too. With so much health information about the dangers of refined foods, processed foods, sugars, grains and alcohol, we really do have lots of resources that we never used to have available to us. There really is no excuse any longer. If you really do not know what a good diet is supposed to be, there are qualified health professionals, such as nutritionists etc, who can help you. If you truly are eating a proper healthy diet and exercising, then you shouldn’t be overweight. If you are doing all the right things, then there could be other underlying issues that need to be addressed by an appropriate healthcare professional. But many times I find that what people think is a healthy diet, or appropriate exercise, is very far from what a healthy diet and appropriate exercise is. It is all about what people have been taught by their family and what their perception of a healthy lifestyle is.

If you do have a gynaecological condition, have a men’s health issue, are having problem with fertility, or just need to get healthier, now is the time to act. We can no longer deny that excess fats are a major concern for the population and are causing so many health issues across the board.

Just so people know, it isn’t necessarily about weight and measuring yourself with scales. Scales do not show the amount of body fat we have and muscles weighs more than fat. We need people to get out the tape measure to truly see how much fat they have and start to look at waist measurement, rather than weight measurement.

A health male needs to have a waist measurement of 94cms or below and a woman needs to have a healthy waist measurement of 80cms or below. If a male has a waist measurement about 94cm or more, or a woman has a waist measurement of 80cms or more, both he and she are at increased risk of health issues. A measurement of above 102 cm (for men) or 88 cm (for women) is one of the components of Metabolic Syndrome, which puts you at increased risk of diabetes, cardiovascular disease and cancers.

Maintaining a healthy lifestyle is vital protection against many of the health issues we face. Regular exercise, limiting alcohol, non-smoking, a nutritious diet, reducing grains and refined foods and stress reduction are all important. The lower GI diets (Primal, Zone etc) have been shown to be much better than others for people who are overweight, obese and have excess body fats. At Shen Therapies we believe that we can give you the best dietary advice available. A healthy diet, nutritional and herbal supplementation has been researched and shown to benefit many people and is a big part of our overall treatment for everybody that comes to see us for help. Please know that we are here to help you, not judge you. Helping you, help yourself have a better life and have better health, is our priority.

Acupuncture Treats, Clears & Prevents Migraines

Acupuncture on skin,Closeup.

 

 

Researchers have successfully documented not only that acupuncture is safe and effective for the relief of migraines, but also how acupuncture achieves positive outcomes.

As a past sufferer (yes past sufferer) of Migraines, I know all too well how debilitating and painful this condition can be when an attack happens. Even when the initial stage of the Migraine subsides, the aura and residual effects can last for days. While pain medication is a much needed part of the process, I also know that if you don’t administer the medication at the right time, the medication sometimes will have little, or no effect, once the migraine takes hold. Worse still, the withdrawal effects of these very strong pain medications can often then induce migraines and headaches, which then require further medication. It really can be a never-ending viscous cycle.

Migraines really do need a multimodality approach to them because the causes of them come from neck dysfunction(sublaxations), diet, blood sugars, hormones, stress and lifestyle. This is why an individual approach is always needed to properly assess, evaluate and treat migraines is needed. Too many people are just patching their condition, with a variety of treatments that really are only just getting them through to the next attack. What people need is a treatment that will not only treat the cause of their migraines, but also help prevent further migraines and give them long term relief and even cure. Acupuncture is just one component in that overall treatment and prevention. So let’s look at how acupuncture can help.

Acupuncture has been shown to induce important biological responses to prevent and alleviate migraines. Imaging studies of the brain using fMRI technology confirm that acupuncture causes specific cortical responses to achieve lasting analgesic effects. In addition, blood level measurements document specific responses to acupuncture that play an important role in preventing and eliminating pain.

Researchers conclude that acupuncture is effective for the prevention and treatment of migraine headaches. A meta-analysis of controlled clinical and laboratory investigations are the basis for the conclusion. In analysis of recent clinical trials, they showed the effectiveness of acupuncture as a treatment for migraines, with less migraine days and less pain intensity levels when acupuncture was administered. Furthermore, no severe adverse effects occurred. A follow-up of up to three months following acupuncture treatments maintained the same results and showed that acupuncture is effective for the treatment of migraines both on the short-term and long-term basis.

In some of the investigation, researchers conducting a clinically-controlled study using fMRI (functional magnetic resonance imaging) where they found a significant decrease in the functional connectivity of the right frontoparietal network of migraine patients. This connectivity dysfunctions was found to be reversible after four weeks of treatment using acupuncture. This is another curative effect of acupuncture that is quantifiable in repeated controlled experiments.

For over 7 thousand years, people have used acupuncture in China for the treatment of various pain conditions, including migraines. It is useful, both as a supplementary treatment and as an alternative treatment, in situations where there is no response to drug therapy. Migraines are a headache disorder affecting a broad population that causes many burdens due to associated healthcare costs and people not being able to go to school and work.

Up to 25% of households in Australia and the United States have at least one member who suffers from migraines. The estimated total number of migraine patients in the United States alone exceeds 28 million and half of them have reduced work or school productivity. In Australia millions of people suffer from Migraines daily and it also affects their work, study and general day to day function, with some not even able to leave their homes due to this debilitating condition.

Scientists have uncovered some of the biochemical mechanisms responsible for acupuncture’s pain killing effects. Drugs used for the treatment of migraines not only have a analgesic action, but they also activate a reaction in the cerebral vessels. In the studies analyzed it was found that acupuncture has been found this very same analgesic action and also activated the same process in the cerebral vessels. The studies revealed acupuncture’s ability to regulate key regions of the brain affected by migraines. The areas are essentially the pain circuitry regions of the brain and cognitive components of pain processing. In addition, acupuncture also restores normal serum nitric oxide (NO) levels that have been found to be almost 55% higher in patients with migraines. Excess NO is a potent vasodilator contributing to headaches and acupuncture restores homeostasis. The regulatory effects of acupuncture can be quantified as early as the fifth acupuncture session and the effects are cumulative.

Based on these and other studies in the meta-analysis, the researchers conclude that acupuncture improves patients’ psychological profile, relieves pain, is safe and cost-effective, and has been found to be at least as effective as conventional preventative pharmacologic treatments for migraines.

At Shen Therapies we know how to treat Migraines properly and also help prevent them returning. We use a multimodaility approach that also give an individualized treatment and also looks at the individuals cause. Our aim is to prevent Migraines from happening in the first place and hopefully prevent them from returning for good. With the right care, this can be done and now research is now backing up what we have known for many years.

References:

Wang Y, Xue CC, Helme R, Da Costa C, Zheng Z (2015) Acupuncture for Frequent Migraine: A Randomized, Patient/Assessor Blinded, Controlled Trial with One-Year Follow-Up. Evid based Complement Alternat Med 2015: 920353.

Da Silva AN (2015) Acupuncture for migraine prevention. Headache 55: 470-473.

Vijayalakshmi I, Sjankar N, Saxena A, Bhatia MS (2014) Coomparison of effectiveness of acupuncture therapy and conventional drug therapy on psychological profile of migraine patients. Indian J Physiol Pharmacol 58: 69-76.

What You Can Eat During Pregnancy

Pregnant belly 2

 

 

 

“What you can eat during Pregnancy”

Earlier this year, I put up a post to see what people thought that you (can) and (can’t) eat during… pregnancy, or if you were trying to fall pregnant. It was really interesting to see what foods people thought you could not eat during pregnancy. It is really interesting that most people want to tell you want you can’t eat, but hardly anyone tells you what you can eat during pregnancy and while trying to fall.

What prompted this post was that a while back I overheard one of my staff and lovely mother to be, talking to another mother to be about what she has been cutting from her diet while she was pregnant and how her food choices were so limited.

I heard all kind of wonderful things from not eating any seafood; not eating any cold meat, not eating soft cheeses, not eating eggs, not eating nuts and nearly the whole food pyramid was being added.

What many people don’t know is that I actually have a background in food science and that I used to teach about bacteria and food hygiene and the nasty consequences of what bacteria can do to the body.

Most pregnant women have the number one fear of foods containing Listeria. It is a rare form of bacteria but it can be fatal (very rare) to a lady if she is pregnant and cause issues such as miscarriage. So not discounting it at all and some countries around the world do not have the food hygiene standards we have here in Australia. We only see about 5 cases per million people in Australia. Basically there is about 0.3-0.4% chance of getting it and we all make such a big deal about it. Again, this is not to discount it either. Listeria can be found in unpasteurised products such as diary and cheese and can be found in some forms of deli meats mainly.

But if a health issues such as Listeria poisoning is so rare, why do we make such a fuss about it and not warn women of other potentially worse factors that cause more cases per year, and can be potentially fatal too. The problem is if women only hear about the foods they can’t eat, many of them are going to be nutrient deficient all for the fear of a tiny chance of listeria causing an issue with a pregnancy.

The truth is, other bacteria such as Salmonella, Shigella and Camphyobacter have a higher rate of infection per year than listeria ever will and nobody ever talks about them. There are over 25,000 cases of these combined and most of the spread is through person to person contact, not just foods themselves. Basically many food poisoning cases are actually from bacteria being on your own hands, which then at some stage end up in, or near your mouth. This is why smokers are at higher risk of food poisoning.

Then we have a far wider implication of gestational diabetes, which account for about 15,000 plus, pregnant women per year, with an annual increase of 5% per year. When someone eats sugary foods, highly processed foods, grains etc during pregnancy, that are a major cause of diabetes, nobody says a thing. Yet mention the word Brie cheese, cold meats etc and everyone goes nuts.

So what do pregnant women really need to know and what can you eat?

Basically the same food hygiene that is needed when you aren’t pregnant is to be observed when you are. There only needs to be a little bit more caution, not an ‘OMG’ stay clear of everything, that unreliable Dr Google, or ‘Someone’, has told you. I would love to know who ‘Someone’ is because he, or she, causes a lot of problems. Remember temperatures between 5 and 60 degrees C are you danger zone area. This is why foods need to be stored below 5 degrees and heated over 60 degrees C.

So what can you eat?

  • So basically you can eat any deli meats as long as they are cryo-vacced and in date. Cryovacced means the air has been taken out and not even bacteria can live in an non-oxygenated environment.
  • You can eat all seafoods as long as they are cooked and fresh.
  • You can eat all cheeses but need to be more careful around the soft cheeses. New research actually shows that small amounts can be beneficial for you. If you cook soft cheeses there is definitely no issue. Just don’t eat cheeses from unpasteurised sources.
  • You can have any form of pasteurised milk or UHT milk.
  • You can have soft serve ice-cream as long as the place you are getting it from looks hygienically clean. Maybe not a good idea to get them from the old ice-cream trucks that aren’t checked regularly by food standards.
  • You can eat nuts and now there is evidence to show that mums not eating nuts during pregnancy may now be the cause of nut allergies.
  • You can definitely eat eggs and you just have to make sure they aren’t raw. Boiled eggs, poached eggs and fried eggs are all fine. Egg custard is fine because it is cooked
  • You can eat all meats if they are cooked and you don’t have to char it until it resembles an old leather shoe. Medium is fine. You just need to cook all chicken right through because all chicken contains salmonella and cooking it kills it.
  • You can have coffee and tea and you just need to limit all caffeine to no more than two cups per day (remember tea has as much caffeine as coffee)

Basically the healthy food pyramid we teach at Shen Therapies needs to be applied.

1. Take our ConceptShen Multivitamin & Omega 3 Oils daily and take a probiotic

2. Eat 2 handful of nuts daily or two tablespoons of healthy oils

3. Limit you grains to one serve (only) per day or cut them completely (best)

4. Eat 2 pieces of low GI fruits per day

5. Protein with every meal or snack

6. 3 serves of veggies or salads per day (just not from a salad bar)

7. 8 glasses of water

8. 2 serves of electrolytes per day when pregnant

9. 30 -45 minutes exercise 2-3 times per week

# No diet drinks or artificial sweeteners at all

Remember food is to be enjoyed and so is pregnancy. Don’t get too caught up in all the worry of what you can’t eat and look more at what you can eat and stick to those foods.

Why Artificial Sweeteners Are Killing You

what if I told you artificial sugars are killing you

 

 

 

 

Recent studies have shown that Artificial Sweeteners increase Obesity, Diabetes, Cardiovascular and Cancer risks and are a major part of one of the many issues slowly killing the us and turning the world population into super obese people.

Right now that can of Coke Zero, diet soda, or Pepsi max doesn’t look so good after all. Neither should it, because the ingredients in those drinks, when consumed, even if just once, or twice per week, are slowing taking years off your life and affecting your health and disrupting your reproductive, metabolic, cardiovascular, endocrine and immunes function.

But it isn’t just these drinks that are the issue. These artificial sweeteners are in are in everything from foods you are eating daily, many popular/fad protein shakes, chewing gum and even kids chewable vitamins. Yes, those vitamins are providing your children with a chemical toxic ingredient on a daily basis, under the banner that it is good for you.

People do need to take the blinkers off and realize that these artificial sugars are in fact a toxic chemical that the body cannot covert properly, tends to store in fat tissue and then covert to other toxic substances in the body. They are worse for you than naturally occurring sugars and that is a scientific and even logical fact. They are chemically engineered and they do not naturally occur in our environment. This doesn’t mean refined sugar is good for you either, but it is definitely better processed by the body and there are better options for sugar than refined sugar cane.

The problem is that most of the population has a sugar addiction and it is slowly killing them, or for some, it is killing them quite quickly. This is not just some conspiracy theory at all. The whole is now facing the fact that most of its population is overweight and resembling the characters off the movie “Wall-E”. But worse still people are now thinking that the chemically laden substitutes are actually a better alternative to sugar. Not so

Consumption of noncaloric, artificially sweetened beverages (ASBs) is associated with an increased risk for disease variety of chronic diseases, according to an opinion article by Susan E. Swithers, PhD, a professor of behavioral neuroscience at Purdue University in West Lafayette, Indiana, publishedin Trends in Endocrinology & Metabolism

In recent years, some high-profile studies have caused concern, suggesting that pregnant women who use high-intensity sweeteners incur risks, including premature delivery. Studies in mice have highlighted cancers related to ingestion of sweeteners in large quantities and potential diabetogenic effects of artificial sweeteners through microbiota.

“Frequent consumers of these sugar substitutes are at increased risk of excessive weight gain, metabolic syndrome, type 2 diabetes, and cardiovascular disease,” Dr. Swithers writes.

The prospective studies Dr. Swithers reviewed found an elevated risk for weight gain and obesity, metabolic syndrome, type 2 diabetes, coronary heart disease, and hypertension in those who consumed ASBs..

Participants who regularly consumed ASBs tended to have higher baseline body mass indexes compared with participants who did not.

Similar studies showed that these artificial sweeteners are also putting children at a major health risk and definitely are a part of the obesity epidemic that is fast turning our children in super obese adults.

Hormones, Brain Response Altered

Brain responses are altered in those who consume artificial sweeteners compared with those who consume caloric sweeteners. In addition, studies in humans have found that the release of hormones and other markers need for hormone synthesis and insulin regulation and glucose homeostasis, are disrupted after ingestion of artificial sweeteners. Many of these artificial sweeteners are actually endocrine disruptors that are affecting the conversion of cholesterol into hormones and causing what many know as “The pregnenolone steal”. Basically you aren’t producing your hormones properly and not converting many of our much-needed hormones at all. Plus obesity is causing hormonal disruption by too much fat, which are now being termed as “Obestrogens”.

Current findings suggest that caution and avoidance of about artificial sweeteners is warranted. People need to open their eyes and look at the foods they are consuming on a daily basis. Many of them have hidden artificial sugars and additives in them and worse still, many of the foods children are consuming daily are the same. We all need to start to eat less process foods, avoid refined sugars, avoid artificial sugars, increase vegetable and fruits, increase nuts and seeds, increase our protein and where possible eat fresh organic foods.

Forget global warming killing us off, the world is doing a pretty good job of its own by ingesting chemically laden foods and sugar substitutes such as these artificial sweeteners.

 

 

Increasing Pregnancy Rates With PGD Testing & Shen Therapies Fertility Program

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Increasing Pregnancy Rates With PGD Testing & Shen Therapies Fertility Program

At least three things are required for a successful pregnancy during in vitro fertilization (IVF): a healthy embryo, a receptive endometrium, and careful transfer at the proper time in the cycle. IVF has improved significantly in its almost 40-year history. Different types of hormone and fertility drugs have been developed that are easier to administer and are associated with an improved safety profile. In addition, numerous stimulation protocols are available that allow us to individually tailor treatments. For example, ultrasound-guided embryo transfer using soft catheters and embryo glue (enzyme to assist implantation) has also helped with ensuring better placement of the embryo, without trauma to the endometrium, but very few clinics are actually doing this. Tests can also be used to evaluate the receptivity of the endometrium in order to determine the best time to schedule the transfer.

Despite all these improvements, however, implantation and pregnancy rates with IVF only slowly increase year after year.

The rate-limiting step of IVF is implantation. It requires the proper interaction of a healthy embryo and a receptive endometrium. It often fails due to problems with the embryos. The genetic health of the embryo depends on both its inherited genetic material and on the errors and repairs during the cell divisions. A chromosomally abnormal embryo is unlikely to implant, and when it does it is likely to be lost early on. Many embryos that are transferred have chromosomal abnormalities, even if they look fine on the outside, or are classified as being the best grade prior to transfer. We need people to understand that just because and embryo has reached Blastocyst, or Morella stage and it looks like a good quality embryo from the outside, it does not mean that the inside and the chromosomes inside the embryo are OK. Not every fertilised egg will result in a genetically sound embryo that will go on to become a baby.

We also need people to realise that an embryo is made up the genetic material of two people and that requires the sperm to be healthy both outwardly, but also chromosomally, and this can change with each batch of sperm ejaculated. Sperm quality and the viability of sperm changes and just because something was “OK” last cycle, or two years ago, or last month, or last week, does not mean that it is OK now. People need to face the reality of what happens with the body and reproduction. The health of the sperm is also reflected in the health and lifestyle and age of the male too. Unhealthy males produce unhealthy sperm and higher levels or sperm with chromosomal abnormalities and damage to the DNA. Unless you are testing every batch of sperm for DNA and chromosomal abnormalities, you aren’t going to see this and even then, testing can only see so much.

A healthy embryo also requires a female to be healthy and her eggs to be health chromosomally and on a DNA level. Egg quality is also related to age, diet, lifestyle, environment, and exposure to environmental disruptors, weight, body fat, stress and so many other factors. We need people to be aware of this. Then when you put two unhealthy people’s genetic and reproductive material together, there is a high likelihood that it will produce higher numbers of abnormal embryos, and sometimes it can be all of them. It all depends on the health of the sperm and health of the eggs at time of fertilisation.

Various methods of genetic testing of embryos have been evaluated in past decades. One can test the chromosome content of the polar bodies, but a cleavage-stage embryo (day 3 of development) or a blastocyst-stage embryo can be evaluated as well. In addition, various techniques  are available for assessing the chromosomes.  There are also new testing and new technologies that have addressed the shortcomings of these earlier tests.

The authors of a recent systematic review concluded that comprehensive genetic screening of embryos using day 5 blastocyst biopsy is associated with increased implantation and pregnancy rates. In addition, this technology appears to be a good tool to limit the number of embryos transferred. But embryos can still be tested early on in their development, with good results, too.

Most experts recommend genetic testing of embryos in women with advanced reproductive age, recurrent implantation failure, recurrent pregnancy loss, or severe male factor infertility/DNA issues. This then gives a greater probability of transferring a chromosomally normal embryo and having a higher chance of implantation and pregnancy occurring. But even a chromosomally normal embryos doesn’t ensure a pregnancy. This is often the hardest thing for people to get their heads around. To be honest, much of this comes down to luck and is really in the hands of the gods.

But what you can do to ensure healthy egg quality, healthy sperm quality, healthy embryo quality, healthy uterine lining, decreases stress levels, optimal health at time of transfer etc, is being on our highly successful fertility program, which has been shown to increase a couples fertility and success rates by 96.1% * ( http://shentherapies.com.au/success-rates/ ) and has helped over 12,000 babies into the world.

For more information on our highly successful fertility program, please call the clinic on 07 32795697, or email us at info@shentherapies.com.au.  You can also visit our website and our web page that explains more about our fertility program as well http://shentherapies.com.au/shen-therapies-highly-successful-fertility-program/

References

  1. Mains L, Van Voorhis BJ. Optimizing the technique of embryo transfer. Fertil Steril. 2010;94:785-790. Abstract
  2. Society for Assisted Reproductive Technology. Clinic Summary Report. https://www.sartcorsonline.com/rptCSR_PublicMultYear.aspx?ClinicPKID=0 Accessed April 27, 2015.
  3. Staessen C, Platteau P, Van Assche E, et al. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial. Hum Reprod. 2004;19:2849-2858. Abstract
  4. Mastenbroek S, Twisk M, van Echten-Arends J, et al. In vitro fertilization with preimplantation genetic screening. N Engl J Med. 2007;357:9-17. Abstract
  5. Yang Z, Liu J, Collins GS, et al. Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study. Mol Cytogenet. 2012;5:24.
  6. Scott RT Jr, Upham KM, Forman EJ, et al. Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertil Steril. 2013;100:697-703. Abstract
  7. Forman EJ, Tao X, Ferry KM, et al. Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates. Hum Reprod. 2012;27:1217-1222. Abstract
  8. Scott RT Jr, Upham KM, Forman EJ, et al. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril. 2013;100:624-630. Abstract